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Recent advances in cancer treatment by iron chelators
Recent advances in cancer treatment by iron chelators Corcé V.; Gouin S.G.; Renaud S.; Gaboriau F.; Deniaud D. Bioorg. Med. Chem. Lett. 2016, 26, 251-256.
The development of new therapeutic alternatives for cancers is a major public health priority. Among the more promising approaches, the iron depletion strategy based on metal chelation in the tumoral environment has been particularly studied in recent decades. The recent efforts to vectorize the chelating agents specifically in the microtumoral environment will be discussed in deta.