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This facility characterizes the size and size distribution of polymers and nano-objects. FFF technology in particular characterizes the size of all nanometric systems ranging from the macro-molecular scale (proteins, polysaccharides, micelles, polymers) to the particle (microparticles, nanoparticles, viruses, etc.).

Characteristics

  • HPLC Shimadzu chain upstream coupled with Channel LC or Frit-inlet channel (Wyatt), membranes possible regenerated cellulose acetate 1, 5 or 10 kD or PES 5 or 10 kD
  • Eclipse fractionation system of Wyatt (the different streams are adjusted according to the type of material to analyze)
  • RI Sopares detector
  • UV detector accordable in wavelength
  • MALS Dawn Eleos Wyatt 18-angle detector

Applications

  • RAMMI – use of polysaccharides coupled with innovative radioisotopes
  • TheraneaM – use of microparticles as carriers of medicine for the processing of large tumors by radionuclide therapy
  • Gadolymph project – use of nanohydrogels encapsulating gadolinium contrast agents for MRI
  • AGuiX® project – use of nanoparticles for PET-MRI

Analysis better suited for materials under 1µm in size, only in an aqueous solution (no organic solvent).

 

Identité
Nom de l’équipement Asymmetric Flow Field Flow Fractionation
Fabriquant de l’appareilWyatt
Nom du lieu d’installationArronax
Nom de l’établissement propriétaireSubatech – Arronax
Type de l’appareilMeasurement of the size and size distribution of nanoparticles and polymers

 

Fonctionnement
Disponibilité de l’équipementAvailable
Appareil en zone réglementéeYes
Contraintes d’utilisationUsers must be trained
Correspondant techniqueContact us