Pre-clinical experimentation and clinical research

This key area is based on network functioning of components distributed between several partners:

Rodent imaging: CIMA (CRCINA, teaching hospital of Nantes)
Imaging of large animals: CEMA (Oniris National veterinary, food processing and food school)
Clinical trials: Department of Nuclear Medicine of the teaching hospital of Nantes and the ICO

Arronax Nantes can thus provide different skills and facilities around pre-clinical imagery of both rodents and medium-sized animals.

Our strengths

First-rate multidisciplinary scientific expertise (biologists, immunologists, radiopharmacists, veterinary surgeons, nuclear doctors, medical physicists)
Translational research: from mice to men
An extended collaboration network (IRON laboratory of excellence, IGO laboratory of excellence, SIRIC ILIAD, etc.)
Experience in public/private collaborative projects
Experience and methodology for clinical trials in nuclear medicine

Collaborative R&D projects
Imaging services
Assistance and provision of facilities for trained users, subject to reservation and invoicing by the hour
Clinical trials (promotion, investigation)
Contractualization of partnerships with scientific, academic and industrial teams.
Confidentiality guaranteed, follow-up and traceability, quality assurance.

Preclinical Evaluation of a 64Cu-Based Theranostic Approach in a Murine Model of Multiple Myeloma, Métivier C, Le Saëc P, Gaschet J, Chauvet C, Marionneau-Lambot S, Hofgaard PO, et al., Pharmaceutics, 25 juin 2023;15(7):1817. https://doi.org/10.3390/pharmaceutics15071817
18F-FDG-Based Radiomics and Machine Learning. Godefroy T, Frécon G, Asquier-Khati A, Mateus D, Lecomte R, Rizkallah M, et al., JACC: Cardiovascular Imaging. avr 2023;S1936878X23000931. https://doi.org/10.1016/j.jcmg.2023.01.020
18ffdg-based radiomics and machine learning: a useful help for aortic prosthetic valve infective endocarditis diagnosis?, Thomas Godefroy, Gauthier Frécon, Antoine Asquier-Khati, Diana Mateus, Raphael Lecomte, Mira Rizkallah, Nicolas Piriou, Thomas Le Tourneau, David Boutoille, Thomas Eugene and Thomas Carlier, European Heart Journal, 43(Supplement 2):ehac544–318, 2022
http://dx.doi.org/10.1093/eurheartj/ehac544.318