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MOOC At the heart of medical radioactivity

The Mooc (Massive Open Online Course) “At the heart of medical radioactivity” of the University of Nantes presents in different stages the interest of medical radioactivity, from the design of a radiopharmaceutical drug to its use in the patient.
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This Mooc, coordinated by Caroline Bodet-Milin and Mickaël Bourgeois and piloted by Marie-Hélène Gaugler and the Service de Production et d’Innovation Numérique (S.P.I.N.) of the University of Nantes, was opened in 2019. It includes 24 episodes, divided into six sections :
Introduction
- History of nuclear medicine (video now unavailable)
- Medical uses of ionizing radiation
What is radioactivity ?
- Journey to the heart of matter (video now unavailable)
- The origins of radioactivity
- The different types of radioactivity
- Concepts in radiobiology
Production of radioactive isotopes
- Cyclotron production: the example of Fluorine-18
- Cyclotron production: the example of Astatine-211
- The neutron reactor: example of Iodine-131 production (video now unavailable)
- Generator production: example of metastable Technetium-99
Radiopharmaceuticals : definition and mode of action
- What is a radiopharmaceutical?
- How radiopharmaceuticals work : the concept of molecular targeting
- Radiopharmaceuticals for diagnostic applications
- Radiopharmaceuticals for therapeutic applications
Medical applications
- Patient pathway – Diagnostic tests in conventional nuclear medicine: an example of bone and myocardial scintigraphy
- Patient pathway – Diagnostic tests using positron emission tomography : example of FDG PET
- Patient pathway – Therapeutic applications : an example of Iodine-131 radiotherapy
- Contribution of nuclear medicine to personalized medicine
- Contribution of nuclear medicine in the management of breast cancer
- Use of ionizing radiation in external radiotherapy
Radioprotection
- Radiation protection : regulatory framework and theoretical data
- Practical radiation protection
- Perception of radioactivity, theoretical data
- The hospitalization experience in a shielded room of patients with thyroid cancer treated with iodine-131