{"id":883,"date":"2018-10-09T08:17:54","date_gmt":"2018-10-09T08:17:54","guid":{"rendered":"https:\/\/www.arronax-nantes.fr\/chimie-et-radiopharmacie\/"},"modified":"2020-02-10T08:12:18","modified_gmt":"2020-02-10T08:12:18","slug":"chimie-et-radiopharmacie","status":"publish","type":"page","link":"https:\/\/www.arronax-nantes.fr\/en\/chimie-et-radiopharmacie\/","title":{"rendered":"Chemistry and radiopharmacy"},"content":{"rendered":"<p>This key area includes research activities ranging from the design to the preparation of radiopharmaceutical products for molecular imagery and targeted radiotherapy.<\/p>\n<p>Upstream, molecular modeling tools and the results of radiochemistry experiments in solution are used for the rational design of new radiopharmaceuticals. Developments in organic and analytical chemistry are conducted for the synthesis of innovative precursors designed to be marked with radioisotopes of interest. Depending on the radioisotope, specific radioactive labeling protocols are drawn up.<\/p>\n<p>Finally, specific GIP Arronax premises (Internal Use Pharmacy Annex, APUI) have been equipped with shielded cells, quality controls instruments and automatic purification, synthesis and distribution systems for radioisotopes and radiopharmaceutical products intended for clinical trials and local and national clinical centers.<\/p>\n<img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-2569 size-large\" src=\"\/wp-content\/uploads\/2018\/10\/IMG_0462-1024x683.jpg\" alt=\"\" width=\"1024\" height=\"683\" srcset=\"https:\/\/www.arronax-nantes.fr\/wp-content\/uploads\/2018\/10\/IMG_0462-1024x683.jpg 1024w, https:\/\/www.arronax-nantes.fr\/wp-content\/uploads\/2018\/10\/IMG_0462-300x200.jpg 300w, https:\/\/www.arronax-nantes.fr\/wp-content\/uploads\/2018\/10\/IMG_0462-768x512.jpg 768w, https:\/\/www.arronax-nantes.fr\/wp-content\/uploads\/2018\/10\/IMG_0462-120x80.jpg 120w, https:\/\/www.arronax-nantes.fr\/wp-content\/uploads\/2018\/10\/IMG_0462-360x240.jpg 360w, https:\/\/www.arronax-nantes.fr\/wp-content\/uploads\/2018\/10\/IMG_0462-111x74.jpg 111w, https:\/\/www.arronax-nantes.fr\/wp-content\/uploads\/2018\/10\/IMG_0462-92x61.jpg 92w, https:\/\/www.arronax-nantes.fr\/wp-content\/uploads\/2018\/10\/IMG_0462-374x249.jpg 374w, https:\/\/www.arronax-nantes.fr\/wp-content\/uploads\/2018\/10\/IMG_0462-599x399.jpg 599w, https:\/\/www.arronax-nantes.fr\/wp-content\/uploads\/2018\/10\/IMG_0462-1280x853.jpg 1280w, https:\/\/www.arronax-nantes.fr\/wp-content\/uploads\/2018\/10\/IMG_0462-1920x1280.jpg 1920w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/>\n<p><strong>Four teams of chemists specialized in complementary fields are involved:<\/strong><\/p>\n<ul>\n<li><a href=\"http:\/\/www.crcina.org\/recherche\/departement-3-nohmad\/equipe-13-nuclear-oncology\/\">the Nuclear Oncology team from the CRCINA laboratory<\/a> (U1232 Inserm) has expertise in organic chemistry and radiopharmacy;<\/li>\n<li>the Radiochemistry and Theory groups from the Subatech laboratory\u00a0(UMR 6457) have skills in experimental and theoretical radiochemistry;<\/li>\n<li>the Ceisam laboratory (UMR 6230 CNRS-University of Nantes) contributes its know-how in molecular modeling (ModES team) and organic synthesis (CORAIL team);<\/li>\n<li>the radiochemists attached to the GIP Arronax APUI contribute their expertise in engineering.<\/li>\n<\/ul>\n<p><strong>\u00a0<\/strong><strong>This consortium is able to draw up cooperation agreements or provide services in the following fields:<\/strong><\/p>\n<ul>\n<li>analysis and purification of organic molecules<\/li>\n<li>radioactive labeling of molecules and biomolecules<\/li>\n<li>scale-up and GMP production of radiopharmaceuticals<\/li>\n<li><a href=\"http:\/\/www.crcina.org\/recherche\/departement-3-nohmad\/equipe-13-nuclear-oncology\/\">l\u2019\u00e9quipe Oncologie nucl\u00e9aire du laboratoire CRCINA<\/a> (U1232 Inserm) poss\u00e8de une expertise en chimie organique et radiopharmacie;<\/li>\n<li><a href=\"http:\/\/www-subatech.in2p3.fr\/fr\/recherche\/nucleaire-et-sante\/radiochimie\/presentation\" target=\"_blank\" rel=\"noopener noreferrer\">les groupes Radiochimie et Th\u00e9orie du laboratoire Subatech<\/a> (UMR 6457) exercent leurs comp\u00e9tences en radiochimie exp\u00e9rimentale et th\u00e9orique;<\/li>\n<li>le <a href=\"http:\/\/www.sciences.univ-nantes.fr\/CEISAM\/\" target=\"_blank\" rel=\"noopener noreferrer\">laboratoire Ceisam<\/a> (UMR 6230 CNRS-Universit\u00e9 de Nantes) participe de son savoir-faire en mod\u00e9lisation mol\u00e9culaire (\u00e9quipe ModES) et en synth\u00e8se organique (\u00e9quipe CORAIL);<\/li>\n<li>les radiochimistes attach\u00e9s \u00e0 l\u2019APUI du GIP Arronax contribuent de leur expertise en ing\u00e9nierie.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>This key area includes research activities ranging from the design to the preparation of radiopharmaceutical products for molecular imagery and targeted radiotherapy. Upstream, molecular modeling tools and the results of radiochemistry experiments in solution are used for the rational design of new radiopharmaceuticals. Developments in organic and analytical chemistry are conducted for the synthesis of innovative precursors designed to be &hellip; <a href=\"https:\/\/www.arronax-nantes.fr\/en\/chimie-et-radiopharmacie\/\" class=\"more\"><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-axe-landing.php","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-883","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Chemistry and radiopharmacy - Arronax Nantes<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.arronax-nantes.fr\/en\/chimie-et-radiopharmacie\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Chemistry and radiopharmacy - Arronax Nantes\" \/>\n<meta property=\"og:description\" content=\"This key area includes research activities ranging from the design to the preparation of radiopharmaceutical products for molecular imagery and targeted radiotherapy. Upstream, molecular modeling tools and the results of radiochemistry experiments in solution are used for the rational design of new radiopharmaceuticals. Developments in organic and analytical chemistry are conducted for the synthesis of innovative precursors designed to be &hellip;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.arronax-nantes.fr\/en\/chimie-et-radiopharmacie\/\" \/>\n<meta property=\"og:site_name\" content=\"Arronax Nantes\" \/>\n<meta property=\"article:modified_time\" content=\"2020-02-10T08:12:18+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.arronax-nantes.fr\\\/en\\\/chimie-et-radiopharmacie\\\/\",\"url\":\"https:\\\/\\\/www.arronax-nantes.fr\\\/en\\\/chimie-et-radiopharmacie\\\/\",\"name\":\"Chemistry and radiopharmacy - Arronax Nantes\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.arronax-nantes.fr\\\/#website\"},\"datePublished\":\"2018-10-09T08:17:54+00:00\",\"dateModified\":\"2020-02-10T08:12:18+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.arronax-nantes.fr\\\/en\\\/chimie-et-radiopharmacie\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.arronax-nantes.fr\\\/en\\\/chimie-et-radiopharmacie\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.arronax-nantes.fr\\\/en\\\/chimie-et-radiopharmacie\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Arronax Nantes\",\"item\":\"https:\\\/\\\/www.arronax-nantes.fr\\\/en\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Chemistry and radiopharmacy\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.arronax-nantes.fr\\\/#website\",\"url\":\"https:\\\/\\\/www.arronax-nantes.fr\\\/\",\"name\":\"Arronax Nantes\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.arronax-nantes.fr\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Chemistry and radiopharmacy - Arronax Nantes","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.arronax-nantes.fr\/en\/chimie-et-radiopharmacie\/","og_locale":"en_US","og_type":"article","og_title":"Chemistry and radiopharmacy - Arronax Nantes","og_description":"This key area includes research activities ranging from the design to the preparation of radiopharmaceutical products for molecular imagery and targeted radiotherapy. 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